The Agroecology and Safe food System Transitions (ASSET) project is a five-year regional project funded by the Agence Française de Développement (AFD), the European Union (EU), and the Fond Français pour l’Environnement Mondial (FFEM). The overall objective of the project is to harness the potential of agroecology to transform food and agricultural systems into more sustainable systems, notably safer, more equitable and inclusive, in Southeast Asia (SEA). The project intervenes in four countries (Cambodia, Laos, Myanmar, and Vietnam). The project is structured in two operational components and six sub-components (Fig. 1). Flagship sites are pilot administratively managed territories where efforts and resources are concentrated to support and document agroecological and safe food system transitions. They are seen as key instruments of the sub-component 2.1 “Knowledge production and support to innovations”. ASSET project will support innovations and knowledge production in four flagship sites, one per country. Fourteen potential flagship sites have been pre-identified during project feasibility, with four potential sites in Cambodia and Laos respectively, three potential sites in Myanmar and Vietnam respectively The present report describes the potential of Xieng Khouang Province as flagship site for agroecology and safe food system transitions in Laos.